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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B3
All Species:
45.15
Human Site:
Y77
Identified Species:
66.22
UniProt:
Q15393
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15393
NP_036558.3
1217
135577
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Chimpanzee
Pan troglodytes
XP_511081
1283
142840
Y143
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001107025
1199
133593
S77
V
I
L
E
Y
Q
P
S
K
N
M
F
E
K
I
Dog
Lupus familis
XP_536791
1217
135545
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q921M3
1217
135532
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Rat
Rattus norvegicus
XP_001077410
1216
135436
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506454
1217
135474
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Chicken
Gallus gallus
XP_001232348
1218
135585
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVE8
1217
135603
Y77
L
T
G
G
T
K
D
Y
V
V
V
G
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728546
1227
136598
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Honey Bee
Apis mellifera
XP_623333
1217
135272
Y77
L
T
G
G
T
K
D
Y
I
V
V
G
S
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188711
1141
126889
I78
D
A
Q
A
R
L
T
I
S
S
P
L
E
A
H
Poplar Tree
Populus trichocarpa
XP_002312063
1213
134429
I77
T
G
A
Q
K
D
Y
I
V
V
G
S
D
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49552
1088
121161
P47
I
E
I
H
L
L
S
P
Q
G
L
Q
T
I
L
Baker's Yeast
Sacchar. cerevisiae
Q04693
1361
153766
E89
L
E
A
G
S
K
R
E
Q
S
Q
L
C
V
A
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
Y83
L
A
G
S
H
K
D
Y
I
I
L
A
T
D
S
Conservation
Percent
Protein Identity:
100
94.8
98.1
99.9
N.A.
99.9
99.5
N.A.
99.6
99
N.A.
93.4
N.A.
75.4
80.5
N.A.
76.1
Protein Similarity:
100
94.8
98.2
100
N.A.
100
99.5
N.A.
99.9
99.6
N.A.
97.9
N.A.
86.9
90.2
N.A.
85.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
100
100
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
0
Percent
Protein Identity:
58.7
N.A.
N.A.
23.5
23
51
Protein Similarity:
76.1
N.A.
N.A.
42
41.5
69.5
P-Site Identity:
6.6
N.A.
N.A.
0
20
53.3
P-Site Similarity:
13.3
N.A.
N.A.
20
33.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
7
0
0
0
0
0
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
7
69
0
0
0
0
0
7
69
0
% D
% Glu:
0
13
0
7
0
0
0
7
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
7
69
69
0
0
0
0
0
7
7
63
0
0
7
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
7
7
0
0
0
0
13
63
7
0
0
0
7
7
% I
% Lys:
0
0
0
0
7
75
0
0
7
0
0
0
0
7
0
% K
% Leu:
75
0
7
0
7
13
0
0
0
0
13
13
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% P
% Gln:
0
0
7
7
0
7
0
0
13
0
7
7
0
0
0
% Q
% Arg:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
7
0
7
7
7
13
0
7
63
7
69
% S
% Thr:
7
63
0
0
63
0
7
0
0
0
0
0
13
0
0
% T
% Val:
7
0
0
0
0
0
0
0
13
69
63
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _